abstract：:Tau plays an important pathological role in a group of neurodegenerative diseases called tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic encephalopathy and corticobasal degeneration. In each disease, tau self-assembles abnormally to form filaments that deposit in the brain. Tau is a nativ...

journal_title：Frontiers in neurology

authors： Oakley SS,Maina MB,Marshall KE,Al-Hilaly YK,Harrington CR,Wischik CM,Serpell LC

更新日期：2020-11-12 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.563609.]. ...

journal_title：Frontiers in neurology

authors： Zhang J,Meng Q,Zhong J,Zhang M,Qin X,Ni X,Ma J,He Y,Zeng D,Lan D

更新日期：2020-11-12 00:00:00

abstract：:Tau accumulation is a prominent feature in a variety of neurodegenerative disorders and remarkable effort has been expended working out the biochemistry and cell biology of this cytoplasmic protein. Tau's wayward properties may derive from germline mutations in the case of frontotemporal lobar degeneration (FTLD-MAPT)...

journal_title：Frontiers in neurology

authors： Kang SG,Eskandari-Sedighi G,Hromadkova L,Safar JG,Westaway D

更新日期：2020-11-12 00:00:00

abstract：:Patients with severe mental illnesses may present extrapyramidal symptoms as part of a concomitant neurological disorder or secondary to medications. Extrapyramidal symptoms are frequently unrecognized, have negative consequences for adherence to treatment, negatively affect quality of life and can induce stigma. We e...

journal_title：Frontiers in neurology

authors： Roiter B,Pigato G,Antonini A

更新日期：2020-11-10 00:00:00

abstract：:This study aimed to assess the efficacy and safety of self-designed Ningxin Anshen (NXAS) Formula for post-ischemic stroke insomnia of blood-deficient and liver-heat syndrome. Ninety patients were randomized into NXAS group, Placebo group and Zopiclone group. Patients in the NXAS group, Placebo group and Zopiclone gro...

journal_title：Frontiers in neurology

authors： Dai N,Li Y,Sun J,Li F,Xiong H

更新日期：2020-11-09 00:00:00

abstract：:Background: Intracranial atherosclerotic stenosis (ICAS) is an important cause of ischemic stroke. In Asians, intracranial atherosclerotic disease leads to 33-50% of ischemic events. At present, treatment with medication vs. endovascular therapy (EVT) for symptomatic ICAS (sICAS) patients is still debatable. The clini...

journal_title：Frontiers in neurology

authors： Zhang J,Zhang K,Jia B,Qi Z,Mo D,Ma N,Gao F,Miao Z

更新日期：2020-11-06 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is mainly associated with preceding exposure to an infectious agent, although the precise pathogenic mechanisms and causes remain unknown. Increasing evidence indicates an association between trauma-related factors and GBS. Here, we performed a systematic review, summarized the current sc...

journal_title：Frontiers in neurology

authors： Huang C,Zhang Y,Deng S,Ren Y,Lu W

更新日期：2020-11-06 00:00:00

abstract：:Seizures are an infrequent and serious neurological complication of SARS-CoV-2 infection, with limited data describing the etiology and the clinical context in which these occur or the associated electrographic and imaging findings. This series details four cases of seizures occurring in patients with COVID-19 with di...

journal_title：Frontiers in neurology

authors： Hwang ST,Ballout AA,Mirza U,Sonti AN,Husain A,Kirsch C,Kuzniecky R,Najjar S

更新日期：2020-11-05 00:00:00

abstract：:Objectives: This article aims to evaluate the safety and effectiveness of endoscope-assisted surgery for chronic subdural hematoma (cSDH) in comparison with the burr-hole craniostomy. Methods: An electronic literature research was performed in MEDLINE, the Cochrane library, and EMBASE from the inception to February 18...

journal_title：Frontiers in neurology

authors： Guo S,Gao W,Cheng W,Liang C,Wu A

更新日期：2020-11-05 00:00:00

abstract：:Epilepsy is a neurological disorder in which, in many cases, there is poor pharmacological control of seizures. Nevertheless, it may respond beneficially to alternative treatments such as dietary therapy, like the ketogenic diet or caloric restriction. One of the mechanisms of these diets is to produce a hyperpolariza...

journal_title：Frontiers in neurology

authors： Rubio C,Luna R,Rosiles A,Rubio-Osornio M

更新日期：2020-11-05 00:00:00

abstract：:Introduction: The purpose of this study was to verify whether the prevalence of intracranial aneurysm (IA) in patients with acoustic neuroma is greater than that in age- and sex-matched controls and to evaluate the independent risk factors related to the occurrence of IA. Methods: We retrospectively analyzed 231 patie...

journal_title：Frontiers in neurology

authors： You H,Bai Y,Yu T,Zeng T,Huang N,Mei W,Jiang C,Kang D,Wu X,Chen F

更新日期：2020-11-02 00:00:00

abstract：:Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the characteristic loss of hand function and spoken language after the first year of life, people with RTT also have a variety of physiological and auton...

journal_title：Frontiers in neurology

authors： Ward CS,Huang TW,Herrera JA,Samaco RC,McGraw CM,Parra DE,Arvide EM,Ito-Ishida A,Meng X,Ure K,Zoghbi HY,Neul JL

更新日期：2020-10-30 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.00696.]. ...

journal_title：Frontiers in neurology

authors： Lin N,Hao H,Guan H,Sun H,Liu Q,Lu Q,Jin L,Ren H,Huang Y

更新日期：2020-10-30 00:00:00

abstract：:Introduction: This study quantified stroke-related changes in the following: (1) the averaged discharge rate of motor units (individually tracked and untracked) identified from high-density electromyography (HD-EMG) recordings, (2) global muscle EMG properties of the dorsiflexors during a fatiguing contraction, and th...

journal_title：Frontiers in neurology

authors： Negro F,Bathon KE,Nguyen JN,Bannon CG,Orizio C,Hunter SK,Hyngstrom AS

更新日期：2020-10-29 00:00:00

abstract：:Objective: To evaluate ocular and cervical vestibular evoked myogenic potentials (oVEMPs and cVEMPs) in patients with solely intracochlear localization of an intralabyrinthine schwannoma (ILS). Study Design: Retrospective analysis of a series of cases. Setting: Monocentric study at a tertiary referral center. Patients...

journal_title：Frontiers in neurology

authors： Fröhlich L,Curthoys IS,Kösling S,Obrist D,Rahne T,Plontke SK

更新日期：2020-10-27 00:00:00

abstract：:Background and Objective: Parkinson disease (PD) with rapid eye movement (REM) sleep behavior disorder (PD-RBD) tend to be a distinct phenotype with more severe clinical characteristics and pathological lesion when compared with PD without RBD (PD-nRBD). However, the pathological mechanism underlying PD-RBD remains un...

journal_title：Frontiers in neurology

authors： Li J,Zeng Q,Zhou W,Zhai X,Lai C,Zhu J,Dong S,Lin Z,Cheng G

更新日期：2020-10-27 00:00:00

abstract：:The electrophysiological EEG features such as high frequency oscillations, spikes and functional connectivity are often used for delineation of epileptogenic tissue and study of the normal function of the brain. The epileptogenic activity is also known to be suppressed by cognitive processing. However, differences bet...

journal_title：Frontiers in neurology

authors： Cimbalnik J,Pail M,Klimes P,Travnicek V,Roman R,Vajcner A,Brazdil M

更新日期：2020-10-27 00:00:00

abstract：:Systemic BCGitis and autoimmune diseases are possible adverse events of intravesical Bacille Calmette-Guérin-(BCG)-instillations in the treatment of urothelioma cancer. We present the case of an 83-years-old male patient with rapid progressive symptoms of dementia up to mutism as well as tonic seizures. Immune-mediate...

journal_title：Frontiers in neurology

authors： Becker A,Grunwald IQ,Unger MM,Behnke S,Spiegel J,Yilmaz U,Walter S,Faßbender K

更新日期：2020-10-26 00:00:00

abstract：:Objective: The aims of the present systematic review were to explore the prevalence of migraine with anxiety exclusively and determine if and why there are likely to be differences across genders. Introduction: Migraine is a very common neurological disorder and cause of productive disability worldwide that is more fr...

journal_title：Frontiers in neurology

authors： Karimi L,Crewther SG,Wijeratne T,Evans AE,Afshari L,Khalil H

更新日期：2020-10-26 00:00:00

abstract：:Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular end-organ disease, and it is one of the first causes of access to the emergency room. The moment of migration of the otoconial debris in a semicircular canal does not necessarily coincide with the moment of detachment of the debris th...

journal_title：Frontiers in neurology

authors： Gufoni M,Vianini M,Casani AP

更新日期：2020-10-23 00:00:00

abstract：:Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more frequently observed in infants of smoking mothers. The global prevalence of smoking during pregnancy is 1.7% and up to 8.1% of women in Europe smoke du...

journal_title：Frontiers in neurology

authors： Bednarczuk N,Milner A,Greenough A

更新日期：2020-10-23 00:00:00

abstract：:Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent retriever (SR) thr...

journal_title：Frontiers in neurology

authors： Chuming H,Yifan H,Ke X,Chukai X,Weijie Z,Hui L,Guoyi P,Xiaoyong Z,Peifeng Z,Chuwei C

更新日期：2020-10-22 00:00:00

abstract：:Chronic subdural hematoma (cSDH) is a common disease process associated with significant morbidity that occurs most often in elderly patients. Asymptomatic patients are typically treated conservatively, with surgical intervention reserved for patients with symptomatic and/or large hematomas that cause brain compressio...

journal_title：Frontiers in neurology

authors： Catapano JS,Nguyen CL,Wakim AA,Albuquerque FC,Ducruet AF

更新日期：2020-10-20 00:00:00

abstract：:Purpose: The use of optical coherence tomography (OCT) of the retina to detect inner retinal degeneration is being investigated as a potential biomarker for mild cognitive impairment (MCI) and Alzheimer's disease (AD), and an overwhelming body of evidence indicates that discovery of disease-modifying treatments for AD...

journal_title：Frontiers in neurology

authors： Mejia-Vergara AJ,Restrepo-Jimenez P,Pelak VS

更新日期：2020-10-16 00:00:00

abstract：:Most blast-induced traumatic brain injuries (bTBI) are mild in severity and culpable for the lingering and persistent neuropsychological complaints in affected individuals. There is evidence that the prevalence of symptoms post-exposure may be sex-specific. Our laboratory has focused on changes in the monoamine and th...

journal_title：Frontiers in neurology

authors： Kawa L,Arborelius UP,Hökfelt T,Risling M

更新日期：2020-10-15 00:00:00

abstract：:Background: Studies have investigated the lipid profile in amyotrophic lateral sclerosis (ALS), including the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and higher low-density lipoprotein (LDL), and the associations with mortality of ALS, but the results were inconsistent. The...

journal_title：Frontiers in neurology

authors： Liu J,Luo X,Chen X,Shang H

更新日期：2020-10-15 00:00:00

abstract：:Background: Prolonged static whole-body roll-tilt has been shown to bias estimates of the direction of gravity when assessed by static paradigms such as the subjective visual vertical and the subjective haptic vertical. Objective: We hypothesized that these shifts are paradigm-independent and thus predicted a post-til...

journal_title：Frontiers in neurology

authors： Wedtgrube A,Bockisch CJ,Straumann D,Tarnutzer AA

更新日期：2020-10-15 00:00:00

abstract：:Objective: The aim of the present observational study is to report on the data from a large sample of inpatients, clinical staff and other workers at an Italian neurorehabilitation hospital dealing with SARS-CoV-2 infections, in order to analyze how it might have affected the management and the effectiveness of neuror...

journal_title：Frontiers in neurology

authors： Salvia A,Morone G,Iosa M,Balice MP,Paolucci S,Grasso MG,Traballesi M,Nocentini U,Formisano R,Molinari M,Rossini A,Caltagirone C

更新日期：2020-10-09 00:00:00

abstract：:Background: Pediatric migraine is among the most common primary or comorbid neurologic disorders in children. Psychological stressors are widely acknowledged as potential triggers involved in recurring episodes of pediatric migraine. As the COVID-19 emergency may have affected the levels of stress perceived by childre...

journal_title：Frontiers in neurology

authors： Dallavalle G,Pezzotti E,Provenzi L,Toni F,Carpani A,Borgatti R

更新日期：2020-10-08 00:00:00

abstract：:Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

journal_title：Frontiers in neurology

authors： Lu H,Wu PF,Li RZ,Zhang W,Huang GX

更新日期：2020-10-07 00:00:00

abstract：:Non-linear relations of brain amyloid beta (Aβ) with task- based functional connectivity (tbFC) measured with functional magnetic resonance imaging (fMRI) have been reported in late middle age. Our objective was to examine the association between brain Aβ and resting-state functional connectivity (rsFC) in late middle...

journal_title：Frontiers in neurology

authors： Tahmi M,Rippon B,Palta P,Soto L,Ceballos F,Pardo M,Sherwood G,Hernandez G,Arevalo R,He H,Sedaghat A,Arabshahi S,Teresi J,Moreno H,Brickman AM,Razlighi QR,Luchsinger JA

更新日期：2020-10-06 00:00:00

abstract：:Purpose: Stroke-associated pneumonia (SAP), a common complication in acute ischemic stroke (AIS) patients, is associated with poor prognosis after AIS. Inflammation plays an important role in the development of SAP. In this study, we aimed to explore the association between the monocyte-to-lymphocyte ratio (MLR) and S...

journal_title：Frontiers in neurology

authors： Cheng HR,Song JY,Zhang YN,Chen YB,Lin GQ,Huang GQ,He JC,Wang Z

更新日期：2020-10-06 00:00:00

abstract：:Several studies have demonstrated the advantages of the bilateral vs. unilateral cochlear implantation in listeners with bilateral severe to profound hearing loss. However, it remains unclear to what extent bilaterally implanted listeners have access to binaural cues, e.g., accurate processing of interaural timing dif...

journal_title：Frontiers in neurology

authors： Ausili SA,Agterberg MJH,Engel A,Voelter C,Thomas JP,Brill S,Snik AFM,Dazert S,Van Opstal AJ,Mylanus EAM

更新日期：2020-09-30 00:00:00

abstract：:Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority. Of particular need is a more concerted effort to employ animal models to determine possible sex differences, which have been reported in the clinical literature....

journal_title：Frontiers in neurology

authors： McCabe JT,Tucker LB

更新日期：2020-09-30 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked recessive neuromuscular disorders caused by mutations in DMD. A high-quality database of DMD/BMD is essential not only for clinical practice but also for fundamental research. Here, we aimed to build the largest Chinese national dystrop...

journal_title：Frontiers in neurology

authors： Tong YR,Geng C,Guan YZ,Zhao YH,Ren HT,Yao FX,Ling C,Wang DC,Chen L,Cui LY,Zhang SY,Dai Y

更新日期：2020-09-30 00:00:00

abstract：:Introduction: Novel therapies are needed for the treatment of motion sickness given the inadequate relief and bothersome and dangerous adverse effects of currently approved therapies. Neurokinin-1 (NK1) receptor antagonists have the potential to be effective in improving the symptoms of motion sickness, given the invo...

journal_title：Frontiers in neurology

authors： Polymeropoulos VM,Czeisler MÉ,Gibson MM,Anderson AA,Miglo J,Wang J,Xiao C,Polymeropoulos CM,Birznieks G,Polymeropoulos MH

更新日期：2020-09-29 00:00:00

abstract：:Background and aims: The pathophysiology of hippocampal enlarged perivascular spaces (H-EPVS) and its relationship to cognitive impairment is largely unknown. This study aimed to investigate the relationship between H-EPVS and cognition in non-dementic elderly population. Methods: A total of 109 subjects were prospect...

journal_title：Frontiers in neurology

authors： Sim JE,Park MS,Shin HY,Jang HS,Won HH,Seo SW,Seo WK,Kim BJ,Kim GM

更新日期：2020-09-29 00:00:00

abstract：:The recurrence rate of chronic subdural hematoma (CSDH) has been reported to range from 2.3 to 33%. As bridging veins are composed of abundant collagen bundles and bone matrix, we aimed to investigate the possible associations between skull Hounsfield unit (HU) values and the recurrence of CSDH. We retrospectively enr...

journal_title：Frontiers in neurology

authors： Ha BJ,Bae IS,Kim JM,Cheong JH,Ryu JI,Han MH

更新日期：2020-09-24 00:00:00

abstract：:Introduction: With the shift of research focus to personalized medicine in Alzheimer's Dementia (AD), there is an urgent need for tools that are capable of quantifying a patient's risk using diagnostic biomarkers. The Medical Informatics Platform (MIP) is a distributed e-infrastructure federating large amounts of data...

journal_title：Frontiers in neurology

authors： Redolfi A,De Francesco S,Palesi F,Galluzzi S,Muscio C,Castellazzi G,Tiraboschi P,Savini G,Nigri A,Bottini G,Bruzzone MG,Ramusino MC,Ferraro S,Gandini Wheeler-Kingshott CAM,Tagliavini F,Frisoni GB,Ryvlin P,Demonet JF,K

更新日期：2020-09-23 00:00:00

abstract：:Alzheimer's disease (AD) is the most prevalent form of late-onset dementia. AD affects the health of millions of people in the United States and worldwide. Currently, there are no approved therapies that can halt or reverse the clinical progression of AD. Traditionally, AD is characterized first by the appearance of a...

journal_title：Frontiers in neurology

authors： Hanslik KL,Ulland TK

更新日期：2020-09-18 00:00:00